Choroidal melanoma recurrence after episcleral brachytherapy and transpupillary thermotherapy

2Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.

Abstract

A 68-year-old man diagnosed with choroidal melanoma (CM) in the right eye underwent treatment with episcleral brachytherapy (I125) and transpupillary thermotherapy. Ultrasound, computed tomography, and magnetic resonance imaging were performed and revealed ocular recurrence of CM. Treatment with extended enucleation was performed. Macroscopic and microscopic examinations revealed extraocular extension and malignant cells, respectively. Immunohistochemistry demonstrated tumoral Melan-A and HMB-45 expression. No cytogenic abnormalities were detected with fluorescence in situ hybridization of tumor cells using probes against chromosomes 3q27 and 8q24. The patient underwent adjuvant external beam radiotherapy for treatment of residual tumor tissue. This case represents the first reported case of recurrent CM with no cytogenetic abnormalities and the absence of metastatic disease, despite a number of the poorest prognostic factors.

Cite

CITATION STYLE

APA

Lantigua-Dorville, Y., Saornil, M. A., García-Alvarez, C., & García-Lagarto, E. (2016). Choroidal melanoma recurrence after episcleral brachytherapy and transpupillary thermotherapy. Arquivos Brasileiros de Oftalmologia, 79(1), 48–49. https://doi.org/10.5935/0004-2749.20160015

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free