Structural maintenance of chromosomes (SMC) proteins form the cohesin and condensin complexes and play important roles in sister chromatid pairing, chromosome segregation, and transcriptional regulation. Two papers in Nature Genetics now show that SMC-like proteins also participate in epigenetic processes such as X inactivation in mammals and RNA-directed DNA methylation in plants. © 2008 Elsevier Inc. All rights reserved.
Heard, E., & Colot, V. (2008, June 10). Chromosome Structural Proteins and RNA-Mediated Epigenetic Silencing. Developmental Cell. https://doi.org/10.1016/j.devcel.2008.05.013