In this issue of Structure, Yoon and colleagues provide models of a low affinity cytokine common receptor, IL-10R2, in a ternary complex with two class II cytokines and their corresponding ligand-specific receptors, revealing the nature of their promiscuous interactions. © 2010 Elsevier Ltd.
Hinck, A. P. (2010, May). Class II cytokine common receptors: Something old, something new. Structure. https://doi.org/10.1016/j.str.2010.04.003