Bone is a hierarchical material that involves fracture mechanisms at multiple scales ranging from nano- to macroscale. The fracture behavior of bone is altered by aging, diseases or therapeutic treatments, therefore, robust predictive methods are necessary to evaluate the changes affecting the fracture risk of bone. Although cohesive modeling has been widely used in various engineering disciplines, it has recently been applied to bone fracture. In this paper, the application of cohesive modeling to the assessment of macro- and microscale fracture mechanisms in bone is presented. The macroscale simulations focus on predicting the fracture risk at the whole bone level whereas the microscale simulations evaluate the influence of microstructural features on crack propagation behavior in bone. These studies demonstrate the strength of cohesive modeling in providing insight into bone's fracture behavior. © 2011 Published by Elsevier Ltd.
Ural, A. (2011). Cohesive modeling of bone fracture at multiple scales. In Procedia Engineering (Vol. 10, pp. 2827–2832). Elsevier Ltd. https://doi.org/10.1016/j.proeng.2011.04.470