Background: There is evidence of the relation between obesity and an increase in prostate-specific antigen, albeit some is contradictory. Aims: Our aim was to compare prostate-specific antigen values in patients with and without abdominal obesity that were seen at the urology service of a tertiary care medical unit, and to analyze the results. Material and methods: A cross-sectional analytic study was conducted within the time frame of June to October 2014. It included first-time urology consultation patients that were referred due to presenting with prostate disease and that had not received medication modifying prostate-specific antigen values. Waist circumference and serum prostate-specific antigen levels were measured. The Student's t test was used for the independent samples and the Pearson and Spearman correlations and the Mann-Whitney U test were used to evaluate the correlation between waist circumference and prostate-specific antigen levels. Results: A total of 110 patients were included that were first-time referrals to the urology service due to prostate pathology. Calculated as means, patient age was 62.6. ± 7.5 years (range: 48-79), waist circumference was 104.5. ±. 10.6. cm (range: 57-130), and prostate-specific antigen level was 3.4. ± 2.5. ng/dl (range: 0.46-21). The mean prostate-specific antigen level was 1.2. ± 6.3. ng/dl (range: 0.46-10.0) for the patients with obesity and 0.4. ± 1.9. ng/dl (range: 1.21-21) for the patients without obesity. Conclusion: There was no statistically significant difference in prostate-specific antigen values in the comparison of the populations presenting with and without obesity.
Osorio-García, M. A., Reyes-García, I. A., & Palacios-Saucedo, G. C. (2015). Comparación de los valores de antígeno prostático específico en pacientes con y sin obesidad abdominal del servicio de urología de una unidad médica de tercer nivel de atención. Revista Mexicana de Urologia, 75(2), 64–71. https://doi.org/10.1016/j.uromx.2015.01.007