Methicillin-resistant Staphylococcus aureus (MRSA) causes serious infections that are even more difficult to treat when associated with a biofilm phenotype that facilitates evasion of the host immune system and antibiotics. As a first step toward understanding the mechanisms underlying biofilm formation, we sequenced the genomes of two prolific biofilm-forming strains belonging to the two most important globally disseminated clonal lineages, USA300 and EMRSA-15.
Sabirova, J. S., Xavier, B. B., Hernalsteens, J. P., De Greve, H., Ieven, M., Goossens, H., & Malhotra-Kumar, S. (2014). Complete genome sequences of two prolific biofilm-forming Staphylococcus aureus isolates belonging to USA300 and EMRSA-15 clonal lineages. Genome Announcements, 2(3). https://doi.org/10.1128/genomeA.00610-14