The article focuses on a study, published in the periodical "PLoS Biology," which uses phenotypic screen to identify pathways that affect feeding behavior in worms. The study, conducted by George Lemieux and colleagues, uses chemoinformatics, in vitro testing, and in vivo assays to observe feeding behavior in Caenorhabditis elegans. It also discusses how the results may be useful for chemoinformatics, and help in improving drug interaction in mammals.
Robinson, R. (2013). From Complex Behavior to New Drugs: Chemoinformatics Shows the Way. PLoS Biology, 11(11). https://doi.org/10.1371/journal.pbio.1001713