Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

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Abstract

Adenosine to inosine (A-to-I) RNA-editing is an essential post-transcriptional mechanism that occurs in numerous sites in the human transcriptome, mainly within Alu repeats. It has been shown to have consistent levels of editing across individuals in a few targets in the human brain and altered in several human pathologies. However, the variability across human individuals of editing levels in other tissues has not been studied so far.

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Greenberger, S., Levanon, E. Y., Paz-Yaacov, N., Barzilai, A., Safran, M., Osenberg, S., … Eisenberg, E. (2010). Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-608

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