Using a fluorescence method called colocalization single-molecule spectroscopy (CoSMoS), Friedman and Gelles dissect the kinetics of transcription initiation at a bacterial promoter. Ultimately, CoSMoS could greatly aid the study of the effects of DNA sequence and transcription factors on both prokaryotic and eukaryotic promoters. © 2012 Elsevier Inc.
Gourse, R. L., & Landick, R. (2012, February 17). CoSMoS unravels mysteries of transcription initiation. Cell. Cell Press. https://doi.org/10.1016/j.cell.2012.01.042