This paper deals with an almost-global stability result for a particular chemostat model. It deviates from the classical chemostat because crowding effects are taken into consideration. This model can be rewritten as a negative feedback interconnection of two systems which are monotone (as input/output systems). Moreover, these subsystems behave nicely when subject to constant inputs. This allows the use of a particular small-gain theorem which has recently been developed for feedback interconnections of monotone systems. Application of this theorem requires - at least approximate - knowledge of two gain functions associated to the subsystems. It turns out that for the chemostat model proposed here, these approximations can be obtained explicitly and this leads to a sufficient condition for almost-global stability. In addition, we show that coexistence occurs in this model if the crowding effects are large enough. © 2006 Elsevier Inc. All rights reserved.
De Leenheer, P., Angeli, D., & Sontag, E. D. (2006). Crowding effects promote coexistence in the chemostat. Journal of Mathematical Analysis and Applications, 319(1), 48–60. https://doi.org/10.1016/j.jmaa.2006.02.036