Cryptococcemia is a bloodstream fungal infection caused by encapsulated yeasts of Cryptococcus neoformans. We reported an 88-year-old woman in whom C. neoformans colonies of smooth and mucoid phenotypes were sequentially cultured from the blood during treatment of retroperitoneal diffuse large B-cell lymphoma using rituximab-containing chemotherapy. The most likely cause was disease progression of pulmonary cryptococcoma. She was successfully treated with optimal antifungal therapy.
Cheng, M. W., Wu, A. Y. J., Liu, C. P., Lim, K. H., Weng, S. L., & Tseng, H. K. (2016). Cryptococcemia in an elderly woman with retroperitoneal diffuse large B-cell lymphoma after rituximab-containing chemotherapy. International Journal of Gerontology, 10(2), 112–116. https://doi.org/10.1016/j.ijge.2015.02.005