An improved methodology for the preparation of copper(I) alkynides has been developed using cesium carbonate as base. In the presence of cesium carbonate and CuI various 1-alkynes were converted smoothly to the corresponding copper alkynides which in situ reacted with propargylic halides in order to synthesize skipped diynes. © 2003 Elsevier Ltd. All rights reserved.
Caruso, T., & Spinella, A. (2003). Cs2CO3 promoted coupling reactions for the preparation of skipped diynes. Tetrahedron, 59(39), 7787–7790. https://doi.org/10.1016/S0040-4020(03)01173-6