The utility of wound débridement has expanded to include the management of all chronic wounds, even in the absence of infection and gross necrosis. Biofilm, metalloproteases on the wound base, and senescent cells at the wound edge irreversibly change the physiology of wound healing and contribute to a pathologic, chronic inflammatory environment. The objective of this review is to provide surgeons with a baseline understanding of the processes of débridement in the noninfected wound. © 2010 Society for Vascular Surgery and the American Podiatric Medical Association.
Cornell, R. S., Meyr, A. J., Steinberg, J. S., & Attinger, C. E. (2010). Délbridement of the noninfected wound. Journal of Vascular Surgery. Mosby Inc. https://doi.org/10.1016/j.jvs.2010.06.006