A CRISPR way to engineer the human genome

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Abstract

RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an effi cient and versatile method for targeted manipulation of mammalian genomes.

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Ramalingam, S., Annaluru, N., & Chandrasegaran, S. (2013). A CRISPR way to engineer the human genome. Genome Biology, 14(2). https://doi.org/10.1186/gb-2013-14-2-107

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