Five New Compounds from the Heartwood of Juniperus formosana hayata

Abstract

Extracts of the heartwood of Juniperus formosana hayata were found to contain the known constituents β-sitosterol, α-cedrol, 4-ketocedrol, 3β-hydroxycedrol, isocedrolic acid, δ-cadinol, cadin-8-en-10-ol, clovandiol, sugiol, Δ5-dehydrosugiol, totarol, 7-oxototarol, cryptojaponol, emodin, and methyl a-conidendral, together with five new compounds, 7a-methoxydeoxocryptojaponol, suginal, detetrahydroconidendrin, formosanol, and junipediol. In addition, 7β-hydroxydeoxocryptojaponoI was obtained (first isolation as a natural product). Junipediol has a novel sesquiterpene skeleton which was elucidated by X-ray analysis. © 1990, The Pharmaceutical Society of Japan. All rights reserved.