Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures

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Abstract

Various studies have shown that brain-derived neurotrophic factor (BDNF) increased neuronal excitability. We tested that BDNF might be involved in the etiology of febrile seizures (FSs). A total of 186 Taiwanese children were divided into two groups: (1) FSs (n = 104); (2) normal control subjects (n = 83). A single base pair polymorphism SNP6265 (Val66Met) at position 196 was analyzed. Our findings suggest that the BDNF polymorphisms were not candidate genetic markers. © 2004 Elsevier B.V. All rights reserved.

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Chou, I. C., Tsai, C. H., Lee, C. C., Lin, S. S., & Tsai, F. J. (2004). Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures. Epilepsy Research, 60(1), 27–29. https://doi.org/10.1016/j.eplepsyres.2004.05.001

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