Small Molecules Restore Telomeres in Patient Stem Cells

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Abstract

Genetic defects in telomere maintenance result in stem cell exhaustion and a spectrum of telomere biology diseases. Systemic treatments beyond organ transplantation are lacking for these diseases. Nagpal and colleagues identified small molecules that restore telomere maintenance in patient-derived stem cells, offering a promising therapy for telomere biology diseases.

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Brenner, K. A., & Nandakumar, J. (2020, August 1). Small Molecules Restore Telomeres in Patient Stem Cells. Trends in Pharmacological Sciences. Elsevier Ltd. https://doi.org/10.1016/j.tips.2020.05.003

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