Hepatic Steatosis Associated with Exposure to Elvitegravir and Raltegravir

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Abstract

Moderate-to-severe hepatic steatosis in people living with human immunodeficiency virus (HIV) without viral hepatitis or excessive alcohol intake was associated with cumulative exposure to stavudine, elvitegravir, and raltegravir. Prospective trials are required to establish a causal association.

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Kirkegaard-Klitbo, D. M., Thomsen, M. T., Gelpi, M., Bendtsen, F., Nielsen, S. D., & Benfield, T. (2021). Hepatic Steatosis Associated with Exposure to Elvitegravir and Raltegravir. Clinical Infectious Diseases, 73(3), E811–E814. https://doi.org/10.1093/cid/ciab057

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