The fragile X: A scanning electron microscope study

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Abstract

Scanning electron microscopy (SEM) has been used to study the fragile X chromosome. The fragile site appears as an isochromatid gap in the majority of cases, confirming light microscope (LM) observations. SEM has allowed a more precise location of the fragile site to the Xq27.3 region.

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Harrison, C. J., Jack, E. M., Allen, T. D., & Harris, R. (1983). The fragile X: A scanning electron microscope study. Journal of Medical Genetics, 20(4), 280–285. https://doi.org/10.1136/jmg.20.4.280

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