Important diagnostic methods of cancer biomarkers related diagnosis and treatment: A review

Abstract

cancer is a serious problem affecting the health of all human societies. thus the challenge is how the diagnosis and then who find effective of treatment . Proto-oncogenes under ubnormal condition turn out to be oncogenes throughout genetic mutation, which is risky and preventing normal cell division and existing. Common mutations of p53 gene controlled on disability of genes for replication. Advance and new molecular approaches that target the tumor cell or the tumor micro-environment was needed. Many molecular techniques like PCR, gene expressions, FISH & CISH,epigenetic signatures and protein biomarker profiles, which in sequence allows to identify the combination of biomarkers which may recognize best the presence or risk of cancer or check cancer therapies. Different techniques used to monitor the biomarker is essential to control the disease. Therefore, this study review aimed to clarification the most common methods used to diagnose the cancer related with some biomarkers.