The clinical outcomes of hemicortical extracorporeal irradiated autologous bone graft after tumor resection of bone and soft tissue sarcoma

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Abstract

Background/Aim: We analyzed the process of healing at osteotomy sites and timing of achievement of full weight-bearing in sarcoma patients who underwent hemicortical or intercalary reconstruction using the extracorporeal irradiated autologous bone graft technique. Patients and Methods: We studied 10 patients who had undergone tumor resection and reconstruction with hemicortical extracorporeal irradiated autologous bone graft at mid-shaft femur or tibia. The control group consisted of 30 patients who received the reconstruction using intercalary bone graft. Results: Full weight-bearing was achieved in all 10 patients at a median time of 4.8 months. Function was excellent in all patients. When comparing the clinical outcome among the patients who received intercalary and hemicortical grafts, the duration to full weight-bearing achievement in patients who received hemicortical graft was shorter than that in those with intercalary graft. Conclusion: Early full weight-bearing may be achieved in patients undergoing hemicortical resection and reconstruction using extracorporeal irradiated autologous bone graft.

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Nakamura, T., Fujiwara, T., Tsuda, Y., Abudu, A., Nomoto, Y., Takada, A., … Sudo, A. (2019). The clinical outcomes of hemicortical extracorporeal irradiated autologous bone graft after tumor resection of bone and soft tissue sarcoma. Anticancer Research, 39(10), 5605–5610. https://doi.org/10.21873/anticanres.13755

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