NemR is a bleach-sensing transcription factor

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Abstract

Background: Little is known about how bacteria sense or respond to reactive chlorine species, such as bleach. Results: NemR is a redox-regulated transcription factor which senses bleach. Conclusion: NemR controls expression of genes encoding electrophile detoxification enzymes, which increase bleach resistance. Significance: We demonstrate a bleach-sensing bacterial response system and a new mechanism contributing to bacterial bleach survival. Copyright © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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Gray, M. J., Wholey, W. Y., Parker, B. W., Kim, M., & Jakob, U. (2013). NemR is a bleach-sensing transcription factor. Journal of Biological Chemistry, 288(19), 13789–13798. https://doi.org/10.1074/jbc.M113.454421

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