FR-900483 is a new immunoactive substance produced by a fungus, Nectria lucida F-4490. Concanavalin A-stimulated lymphocyte proliferation, which had been suppressed by addition of immunosuppressive factor, was restored to a normal level by the addition of FR-900483. Furthermore, FR-900483 restored the capacity of immunosuppressed mice to produce antibody against sheep red blood cells. © 1988, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
CITATION STYLE
Shibata, T., Nakayama, O., Tsurumi, Y., Okuhara, M., Terano, H., & Kohsaka, M. (1988). A new immunomodulator, FR-900483. The Journal of Antibiotics, 41(3), 296–301. https://doi.org/10.7164/antibiotics.41.296
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