CYP2B6 18492T→C polymorphism compromises efavirenz concentration in coinfected HIV and tuberculosis patients carrying CYP2B6 haplotype *1/*1

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Abstract

40 copies/ml and developed efavirenz-associated mutations (P = 0.254). In summary, the CYP2B6 18492T→C polymorphism compromises efavirenz concentrations in patients who carry CYP2B6 haplotype *1/*1 and are coinfected with HIV and tuberculosis. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Manosuthi, W., Sukasem, C., Thongyen, S., Nilkamhang, S., Manosuthi, S., & Sungkanuparph, S. (2014). CYP2B6 18492T→C polymorphism compromises efavirenz concentration in coinfected HIV and tuberculosis patients carrying CYP2B6 haplotype *1/*1. Antimicrobial Agents and Chemotherapy, 58(4), 2268–2273. https://doi.org/10.1128/AAC.02384-13

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