Autophagy: Suicide Prevention Hotline for the Gut Epithelium

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Abstract

Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggered IBD (Burger et al., 2018; Matsuzawa-Ishimoto et al., 2017; Pott et al., 2018). Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggered IBD (Burger et al.; Matsuzawa-Ishimoto et al.; Pott et al.).

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Grizotte-Lake, M., & Vaishnava, S. (2018, February 14). Autophagy: Suicide Prevention Hotline for the Gut Epithelium. Cell Host and Microbe. Cell Press. https://doi.org/10.1016/j.chom.2018.01.015

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