Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.
CITATION STYLE
Cerna-López, J. A., Tejada-Llacsa, P. J., Valle-Farfán, F. A. de J., Alarcón, G. S., Ugarte-Gil, M. F., & Pimentel-Quiroz, V. R. (2023). Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review. Revista Colombiana de Reumatologia, 30(3), 277–282. https://doi.org/10.1016/j.rcreu.2021.06.001
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