Abstract
A most able label: Labeled aptamers (see picture) can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes can be enriched in vitro, from a cellular lysate and from the surface of living cells, opening new ways to study aptamer interactions in biological contexts. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Vinkenborg, J. L., Mayer, G., & Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angewandte Chemie - International Edition, 51(36), 9176–9180. https://doi.org/10.1002/anie.201204174
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