Data on publications, structural analyses, and queries used to build and utilize the AlloRep database

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Abstract

The AlloRep database (www.AlloRep.org) (Sousa et al., 2016) [1] compiles extensive sequence, mutagenesis, and structural information for the LacI/GalR family of transcription regulators. Sequence alignments are presented for >3000 proteins in 45 paralog subfamilies and as a subsampled alignment of the whole family. Phenotypic and biochemical data on almost 6000 mutants have been compiled from an exhaustive search of the literature; citations for these data are included herein. These data include information about oligomerization state, stability, DNA binding and allosteric regulation. Protein structural data for 65 proteins are presented as easily-accessible, residue-contact networks. Finally, this article includes example queries to enable the use of the AlloRep database. See the related article, “AlloRep: a repository of sequence, structural and mutagenesis data for the LacI/GalR transcription regulators” (Sousa et al., 2016) [1].

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Sousa, F. L., Parente, D. J., Hessman, J. A., Chazelle, A., Teichmann, S. A., & Swint-Kruse, L. (2016). Data on publications, structural analyses, and queries used to build and utilize the AlloRep database. Data in Brief, 8, 948–957. https://doi.org/10.1016/j.dib.2016.07.006

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