This data article presents datasets associated with the research article entitled “Generation of matched patient-derived xenograft in vitro–in vivo models using 3D macroporous hydrogels for the study of liver cancer” (Fong et al., 2018) . A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes.
Fong, E. L. S., Toh, T. B., Lin, Q. X. X., Liu, Z., Hooi, L., Rashid, M. B. M. A., … Yu, H. (2018). Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel. Data in Brief, 18, 594–606. https://doi.org/10.1016/j.dib.2018.03.045