Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel

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Abstract

This data article presents datasets associated with the research article entitled “Generation of matched patient-derived xenograft in vitro–in vivo models using 3D macroporous hydrogels for the study of liver cancer” (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes.

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Fong, E. L. S., Toh, T. B., Lin, Q. X. X., Liu, Z., Hooi, L., Rashid, M. B. M. A., … Yu, H. (2018). Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel. Data in Brief, 18, 594–606. https://doi.org/10.1016/j.dib.2018.03.045

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