Endoprosthesis reconstruction, as a surgical treatment of children and adolescence with bone tumors around the knee

Abstract

Aim: analysis of own experience in endoprosthesis reconstruction of the knee for children and adolescents with primary bone tumors. The article reports the results of 65 endoprosthesis reconstruction of the knee joint in children and adolescents with oncological pathology for a 5-year period (2012-2017). The study was approved by the Independent Ethics Committee of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology. Evaluation of functional results was performed using the MSTS scale 3 months after the operation. Postoperative complications were analyzed according to the Henderson classification. The average indicator of the functional rate after operative treatment, according to the MSTS scale, was 76%. The most common postoperative complications were structural failures (7.6%) and infectious complications (6.2%). Overall survival in the largest group of patients with osteosarcoma (56 patients) was 82 ± 12%, event-free survival 37 ± 12%. The use of individual expandable endoprostheses makes it possible to perform operations for patients with skeletal immaturity. Endoprosthesis replacement provide good oncological and functional results, and also contribute to the most adequate social adaptation of the child.