Direct electrical stimulation for epilepsy: The laboratory evidence

Abstract

Studies of deep brain stimulation in laboratory models of seizures and epilepsy are invaluable for understanding of mechanisms of stimulation and for identifying best targets and parameters of stimulation. Recent successes of clinical trials may give more impetus to laboratory studies, which in turn will further our clinical practice. For an expanded treatment of this topic see Jasper's basic mechanisms of the epilepsies. 4th ed. (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at). © 2010 International League Against Epilepsy.