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Drosophila protamine-like Mst35ba and Mst35bb are required for proper sperm nuclear morphology but are dispensable for male fertility

G3: Genes, Genomes, Genetics (2014) 4(11) 2241-2245
DOI: 10.1534/g3.114.012724
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Abstract

During spermiogenesis, histones are massively replaced with protamines. A previous report showed that Drosophila males homozygous for a genomic deletion covering several genes including the protamine-like genes Mst35Ba/b are surprisingly fertile. Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility.

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Tirmarche, S., Kimura, S., Sapey-Triomphe, L., Sullivan, W., Landmann, F., & Loppin, B. (2014). Drosophila protamine-like Mst35ba and Mst35bb are required for proper sperm nuclear morphology but are dispensable for male fertility. G3: Genes, Genomes, Genetics, 4(11), 2241–2245. https://doi.org/10.1534/g3.114.012724

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