GFP expression alters osteosarcoma cell biology

14Citations
Citations of this article
13Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Green fluorescent protein (GFP) expression is widely used for tracking of cells in vivo. Three human osteosarcoma cell lines were transfected with GFP and analyzed for expression of tissue markers and physiology. GFP-mediated increased tumor aggression in vivo in one cell line was corroborated by altered expression of bone markers and osteoblast-like cell biology in vitro as a result of transfection. The use of GFP for cell tracking in osteosarcoma animal models should therefore be used with caution. © Mary Ann Liebert, Inc.

Cite

CITATION STYLE

APA

Dass, C. R., & Choong, P. F. (2007). GFP expression alters osteosarcoma cell biology. DNA and Cell Biology, 26(8), 599–601. https://doi.org/10.1089/dna.2006.0531

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free