Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS): A Case Series

Abstract

Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection (PANDAS) is rare neuropsychiatric syndrome characterized mainly by abrupt onset obsessive compulsive disorder and tic disorder following recent Streptococcal infection. Lack of awareness regarding the disorder leads to less number of recorded clinical cases in the literature. Here, we report a series of three cases of PANDAS associated with features of obsessive compulsive disorders and tic disorder with clinical discussion. All these three cases were positive for antistreptococcal antibody titer and history of recent streptococcal infection.