Analytical methodologies for determination of telmisartan: An overview

Abstract

Telmisartan, an angiotensin II receptor antagonist, is used for the treatment of essential hypertension; the drug has fewer side effects compare to Angiotensin converting enzyme inhibitors. Telmisartan has been determined in formulations and biological fluids by a variety of methods such as spectrophotometry, High-performance liquid chromatography with ultraviolet and flourimetry detection, liquid chromatography coupled with tandem mass spectrometry, densitometry, immune assay methods and electrochemical methods such as hydrogen wave polarography. The overview includes the most relevant analytical methodologies used in its determination since the origin still today.