Delivery of drugs and macromolecules to mitochondria

Citations of this article
Mendeley users who have this article in their library.
Get full text


Mitochondria is where the bulk of the cell's ATP is produced. Mutations occur to genes coding for members of the complexes involved in energy production. Some are a result of damages to nuclear coded genes and others to mitochondrial coded genes. This review describes approaches to bring small molecules, proteins and RNA/DNA into mitochondria. The purpose is to repair damaged genes as well as to interrupt mitochondrial function including energy production, oxygen radical formation and the apoptotic pathway. © 2007 Elsevier B.V. All rights reserved.




Mukhopadhyay, A., & Weiner, H. (2007, August 10). Delivery of drugs and macromolecules to mitochondria. Advanced Drug Delivery Reviews.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free