Peptide receptor radionuclide therapy (PRRT) plays an important role in the treatment of neuroendocrine tumors (NET). Pre-therapeutic dosimetry using the area under the measured time-activity curve (AUC) is important. The sampling schedule for this dosimetry determines the accuracy and reliability of the obtained AUC.
Maaß, C., Sachs, J. P., Hardiansyah, D., Mottaghy, F. M., Kletting, P., & Glatting, G. (2016). Dependence of treatment planning accuracy in peptide receptor radionuclide therapy on the sampling schedule. EJNMMI Research, 6(1). https://doi.org/10.1186/s13550-016-0185-8