Neuropsychiatric sequelae of early nutritional modifications: A beginner’s guide to behavioral analysis

4Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Early parental nutritional interventions during prenatal development have been shown to result in neuropsychiatric sequelae in the adult offspring. In order to understand the impact of such nutritional interventions, the behavior of the animal has to be carefully analyzed. This chapter provides a step-by-step guide to conduct behavioral tests in adult mice for investigators without specific expertise or those without the equipment to carry out behavioral studies. We focus on tests tapping into the main behavioral abnormalities that correspond to mental illnesses. We describe the materials required and the detailed methods to conduct global assessment of parameters such as behavioral integrity and general well-being, psychomotor activity, social behavior, repetitive behavior, anxiety-like behavior, depression-like behavior, short-term spatial working memory, and spatial reference memory.

Cite

CITATION STYLE

APA

Kraeuter, A. K., Guest, P. C., & Sarnyai, Z. (2018). Neuropsychiatric sequelae of early nutritional modifications: A beginner’s guide to behavioral analysis. In Methods in Molecular Biology (Vol. 1735, pp. 403–420). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7614-0_28

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free