Recent studies of acute lymphoblastic leukemia have identified activating mutations in components of the interleukin-7 receptor complex (IL7R, JAK1, and JAK3). It will be of interest to investigate both JAK1 and JAK3 kinase inhibitors as targeted agents for these leukemias.
CITATION STYLE
Degryse, S., & Cools, J. (2015). JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia. Journal of Hematology and Oncology, 8(1). https://doi.org/10.1186/s13045-015-0192-7
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