What a Difference a Phosphate Makes: Life or Death Decided by a Single Amino Acid in MDM2

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Abstract

In this issue of Cancer Cell, Gannon and colleagues create genetically engineered mice to test the role phosphorylation plays in the modification of one serine long thought to play a critical role in controlling the activity of MDM2, one of p53's main negative regulators. © 2012 Elsevier Inc.

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Li, Y. C., & Wahl, G. M. (2012, May 25). What a Difference a Phosphate Makes: Life or Death Decided by a Single Amino Acid in MDM2. Cancer Cell. https://doi.org/10.1016/j.ccr.2012.04.033

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