Previous studies have shown that two hemolytic toxins, HlyA and AerA, contribute to the virulence of Aeromonas hydrophila. A survey was performed to gauge the distribution of hlyA and aerA genes in clinical and environmental Aeromonas isolates. For A. hydrophila, A. veronii biotype sobria and A caviae, 96%, 12% and 35% of strains, respectively, were hlyA positive, whereas, 78%, 97%, 41%, respectively, were aerA positive. All virulent A. hydrophila isolates were hlyA+ aerA+. This genotype was most common in A. hydrophila (75.4%) followed by A. caviae (29.4%) and A. veronii biotype sobria (9.6%). For A. hydrophila, a two-hemolytic toxin model of virulence provides the best prediction of virulence in an animal model. Copyright (C) 1999 Federation of European Microbiological Societies.
CITATION STYLE
Heuzenroeder, M. W., Wong, C. Y. F., & Flower, R. L. P. (1999). Distribution of two hemolytic toxin genes in clinical and environmental isolates of Aeromonas spp.: Correlation with virulence in a suckling mouse model. FEMS Microbiology Letters, 174(1), 131–136. https://doi.org/10.1016/S0378-1097(99)00130-5
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