Renin regulates blood pressure and fluid volume. In this issue of Cell Metabolism, Grobe et al. (2010) provide convincing evidence for a new role for brain renin in metabolic rate and weight loss. Renin overexpression or deletion peripherally from other studies suggests the opposite effect. © 2010 Elsevier Inc.
Luft, F. C. (2010, November 3). Divergent effects of central and peripheral renin on body weight and metabolism. Cell Metabolism. Cell Press. https://doi.org/10.1016/j.cmet.2010.10.009