Automated Technology for Performing Flow-Chemistry at Elevated Temperature and Pressure

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Abstract

Over the past few years, a series of novel microfluidic-based instruments were developed by ThalesNano, Inc. to carry out dangerous and difficult to perform chemical reactions in a safe and fast manner, resulting in superior performance to what commercial batch reactors could provide. Importance of microfluidic devices is continuously raising, as seen there are more and more publications, applications and devices in this field expanding the borders of chemistry. Furthermore, as one of the main advantages for pharmaceutical applications, these new revolutionary reactors allow the fast, on-the-fly mode optimization of different heterogeneous reactions in a high-throughput fashion. The heart of the reactor systems is the actual reactor bed, called the CatCart system. CatCarts allow easy handling of heterogeneous catalyst or immobilized reagents without further purification of products. In addition, the shoe-box size of these reactors makes them available from laboratories to industrial applications. © 2007, Society for Laboratory Automation and Screening. All rights reserved.

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Kovacs, I., Jones, R. V., Niesz, K., Csajagi, C., Borcsek, B., Darvas, F., & Urge, L. (2007). Automated Technology for Performing Flow-Chemistry at Elevated Temperature and Pressure. Journal of Laboratory Automation, 12(5), 284–290. https://doi.org/10.1016/j.jala.2007.06.009

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