Comparative investigation of the sensitivity of Candida fungi isolated from Vulvovaginal candidiasis to nystatin and Teucrium polium smoke product

Abstract

Objectives: The present study aimed to compare the antifungal activities of Teucrium Polium smoke product and nystatin in the treatment of Candida vaginitis in vitro. Materials and Methods: In this quasi-experimental study, 105 subjects were diagnosed with Candida vaginitis. The data were collected through a collection form and the species were isolated by the germ tube, as well as CHROMagar chromogenic and chlamydospore formation tests. Results: Based on the results of the germ tube, chlamydospore formation, and CHROMagar tests, 70.5%, 23.8%, and 66.6% of the species were Candida albicans, respectively. In addition, 99% of the samples were sensitive to nystatin. A significant relationship was also observed between the antifungal drug and the type of organism (P<0.02). Finally, all the 15 standard clinical samples were sensitive to T. polium smoke. Conclusions: In general, the results confirmed the antifungal effects of T. polium and nystatin on the species isolated from 10 clinical samples obtained from Candida vaginitis as well as on five standard strains.