Organ Regeneration 3D Stem Cell Culture & Manipulation

  • Tsuji T
ISSN: 1940-6029
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Abstract

Three-dimensional organogenesis in vivo is principally regulated by the spatiotemporal developmental process that relies on the cellular behavior such as cell growth, migration, differentiation, and cell-to-cell interaction. Organ development and morphogenesis have been elucidated to be regulated by the proper transient expression of various signaling molecules including cytokines, extracellular matrix, and adhesion molecules based on the epithelial and mesenchymal interactions. Current bioengineering technology for regenerating three-dimensional organ has progressed to the replication of organogenesis, thereby enabling the development of fully functional bioengineered organs using bioengineered organ germs that are generated from immature stem cells via tissue engineering technology in vitro.

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APA

Tsuji, T. (2017). Organ Regeneration 3D Stem Cell Culture & Manipulation. Methods in Molecular Biology, 1597(March), 67–83.

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