Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone

Abstract

The flowchart of the localization of phosphorothioate d(GPSA) RP and mass spectra of isolated and synthetic d(GPSA) RP. The fragmentation of d(GPSA) RP is shown in the structural inset, with the [M+H] at m/z 597 in positive mode [1]. Figure 1. The flowchart of the localization of phosphorothioate d(GPSA) RP and mass spectra of isolated and synthetic d(GPSA) RP. The fragmentation of d(GPSA) RP is shown in the structural inset, with the [M+H] at m/z 597 in positive mode [1] … A) Physical maps of S. lividans 1326 and mutant ZX1. The ca. 90 kb region present …