Role of CBNAAT in the Diagnosis of Extra-Pulmonary Tuberculosis: Experience from a Tertiary Care Hospital in India

Abstract

ABBREVIATIONS USED IN THIS ARTICLE MTB = Mycobacterium tuberculosis RIF = Resistance of rifampin CBNAAT = Cartridge-based nucleic acid amplification test DMC = Designated Microscopy Centre AFB = Acid-fast bacilli TB = Tuberculosis CRS = Composite reference standard HIV = Human immunodeficiency virus EPTB = Extra-pulmonary TB CI = Confidence interval LJ = Lowenstein-Jensen ICMR = Indian Council of Medical Research PPV = Positive predictive value NPV = Negative predictive value LNA = Lymph node aspirate CSF = Cerebrospinal fluid WHO = World Health Organization Abstract Background. Xpert-MTB/RIF assay or Cartridge-Based Nucleic Acid Amplification Test (CBNAAT) helps in rapid diagnosis of tuberculosis (TB).