Expanding the Spectrum of Light-Driven Peroxygenase Reactions

Abstract

Peroxygenases require a controlled supply of H 2 O 2 to operate efficiently. Here, we propose a photocatalytic system for the reductive activation of ambient O 2 to produce H 2 O 2 which uses the energy provided by visible light more efficiently based on the combination of wavelength-complementary photosensitizers. This approach was coupled to an enzymatic system to make formate available as a sacrificial electron donor. The scope and current limitations of this approach are reported and discussed.