FORMULATION DEVELOPMENT OF ORO-DISPERSIBLE TABLETS OF AYURVEDIC POWDER FORMULATION FOR EFFICIENT USE

Abstract

The aim of this study was to formulate mouth dissolving tablets from Ayurvedic polyherbal powder Sitopaladi. Sitopaladi is a traditional Ayurvedicpowder preparation well known and effective in relieving coughs associated with various respiratory disorders. Being a powder the administration ofaccurate dose with ease is a problem. Furthermore it needs water and chances of spoilage and waste are more. Oro-dispersible tablet which rapidlydisintegrating in mouth will be the best remedy for efficient use of Sitopaladi. Using various excipients like super-disintegrants and sweeteners, different formulation of anti-tussive drug Sitopaladi were formulated by direct compression method. The acceptable formulation, among all thedeveloped formulations of oro-dispersible tablet was having a disintegrating time of 1 min and 30 sec and acceptable taste. Thus the study concludesthat formulation of oro-dispersible tablets of ayurvedic powder preparation can be a good option to enhance acceptability, efficiency and easy andaccurate administration of powder ayurvedic preparations like Sitopaladi.