The Possible Protective Role of Vitamin C against Toxicity Induced by Lead Acetate in Liver and Spleen of Adult Albino Rats (Light and Electron Microscopic Study)

Abstract

Background: lead toxicity has been recognized as a major environmental health hazard worldwide affecting both humans and animals at all ages especially young children in humans. Lead does not have any beneficial biological effects to humans and its presence at high concentrations produce very undesirable toxic consequences to humans affecting all the body organs. Ascorbic acid is probably the most widely studied vitamin when it helps to prevent lead induced oxidative stress. Its property of quenching ROS along with metal chelation makes it a potential detoxifying agent for lead.